KEGG pathway analysis further highlighted tumor- and inflammation/hypoxia-related pathways, including TNF signaling pathway, IL-17 signaling pathway, HIF-1 signaling pathway, basal cell carcinoma, and PPAR signaling pathway (Fig. 7D), suggesting that this population is involved not only in proliferation but also in the reprogramming of inflammatory and stress-response networks. The gene discussed is TNF; the disease is basal cell carcinoma.