KCNB1 and endometrial cancer: Among Kv channels, Kv2.1 (encoded by KCNB1 gene) displays a role in various tumors including gastric [22] and endometrial cancer [23], in which Kv2.1 forms complexes with other homo-multimer functional channels such as Kv9.3 that modulate the electrophysiological properties of excitable cells, exerting a potential oncogenic role [24].