We found that the glucose deprivation concentration-dependently increased Ser829 phosphorylation of KDM6A in squamous cancer cells HN6 and CAL27 (Fig. 2C and Supplementary Fig. 1D), as well as the B16 melanoma cell and HepG2 hepatocellular carcinoma cell (Fig. 2D and Supplementary Fig. 1E). This evidence concerns the gene KDM6A and melanoma.