The parallel functions between DIM-3,5 analogs and quercetin can also be extended to their effects on ferroptosis since DIM-3,5-CI2 and DIM-3-CI-5-CF3 induce ROS, lipoperoxidation and MDA formation and also decrease expression of GPX4 and SLC7A11 in TNBC cell lines and similar results have been observed for other flavonoids in cancer cells [25–29]. Here, GPX4 is linked to cancer.