FHL3 and hepatocellular carcinoma: In accordance with the differences in the endogenous expression of FHL3 in HCC cell lines, Hep3B and Huh7 cell lines with low endogenous expression of FHL3 were selected to construct FHL3 overexpressing cell lines, and MHCC97H and HLF cell lines with high endogenous expression of FHL3 were constructed to construct FHL3-stable knockdown cell lines (Fig. 2B, C).