Analyses of two RMS patient cohorts show that both genes were upregulated in RMS patients compared to normal skeletal muscle tissues, regardless of the fusion status, with the exception of the expression of UBA3, which was higher in FP-RMS vs FN-RMS patients in one of the two datasets analyzed, in line with the heterogeneity of the tumor (Supplementary Fig. S1A, B). This evidence concerns the gene UBA3 and neoplasm.