The treatment of AZD9291 alone did not affect BRD4, APT1, YAP1, and p-YAP1 and MST1 palmitoylation in tumor cells, whereas the treatment of NHWD870 alone reduced the expression of BRD4, APT1 and YAP1 but enhanced YAP1 phosphorylation and MST1 palmitoylation (Fig. 7C, D). The gene discussed is BRD4; the disease is neoplasm.