TRERF1 and myeloid sarcoma: Likewise, in a model of relapsing-remitting (RR) MS that mimics aspects of cyclic disease observed in MS patients, near-complete protection was observed in mice treated with MPs containing Rapa and proteolipid protein (PLP)—the disease-associated antigen in RR-EAE (Fig. 2G and SI Appendix, Fig. S4D).