DEP elevated in BC includedbeta-glucuronidase isoform 1, fibrinogen gamma chain, alpha-actinin-1,peptidase inhibitor 16, cysteine-rich C-terminal protein 1 isoformX1, guanine nucleotide-binding protein G­(I)/G­(S)/G­(T) subunit beta-1,vascular cell adhesion protein 1, ATP-dependent translocase ABCB1,and tumor protein p63-regulated gene 1 isoform X1. Here, PI16 is linked to breast cancer.