NR3C2 and heart failure: We searched PubMed, EMBASE and the Cochrane Central Register of Controlled Trials (CENTRAL) for reports published before March 31, 2025 using the search terms “glucagon-like peptide 1 receptor agonists (GLP-1 RAs)”, “sodium glucose cotransporter 2 inhibitors (SGLT2i), “steroidal or non-steroidal mineralocorticoid receptor antagonists”, and “mineralocorticoid receptor antagonists (MRAs)”, “randomized controlled trials”, “death”, “heart failure (HF)”, “hospitalization for heart failure”, and “death form cardiovascular causes”.