EMPG has a certain effect on improving cardiac fibrosis and promoting the reversal of ventricular remodeling; detection of WB and PCR of PPARα-related signaling and GLUT4 glucose metabolism pathway in myocardial tissues of rats with HF confirms that the expression of lipid metabolism signaling protein decreases, and glucose metabolism signaling protein expression is impaired in the early stage of HF. Here, SLC2A4 is linked to hydrops fetalis.