Albumin–bilirubin (ALBI) grading—computed from serum albumin and bilirubin with grade 1–3 cut-offs—has reproducible prognostic value and, by avoiding subjective ascites/encephalopathy items in Child–Pugh, offers a more objective baseline; AI models that ingest serial labs can project individualized ALBI trajectories and event-risk horizons (Kim et al., 2024; Zha et al., 2025; Bartholomä et al., 2025). The gene discussed is ALB; the disease is Ascites.