In 2019, a review [42] summarized some specific species closely related to oral cancer, such as Streptococcus sp., Prevotella sp., Fusobacterium sp., and P. gingivalis. Regarding the role of OM in the oncogenic process, three mechanisms have been postulated, including bacteria-stimulating chronic inflammation, bacteria-activating NF-κB and bacteria-inhibiting apoptosis, and bacteria-producing carcinogens. Here, NFKB1 is linked to lip and oral cavity carcinoma.