PTGS2 and Hepatic fibrosis: In the subsequent analysis, 196 hub genes associated with liver fibrosis were identified, including AKT1, IL6, TNF, TP53, VEGFA, JUN, IL1B, EGFR, CASP3, PTGS2, MYC, ESR1, STAT3, HIF1A, MMP9, and EGF.