Additionally, in the hepatic fibrosis mouse model, fibrotic liver tissues exhibited marked upregulation of EGFR, p-JAK1/JAK1, and p-STAT3/STAT3 protein expression (P < 0.01), accompanied by increased phosphorylation of JAK1 and STAT3 (P < 0.01). This evidence concerns the gene EGFR and Hepatic fibrosis.