In the subsequent analysis, 196 hub genes associated with liver fibrosis were identified, including AKT1, IL6, TNF, TP53, VEGFA, JUN, IL1B, EGFR, CASP3, PTGS2, MYC, ESR1, STAT3, HIF1A, MMP9, and EGF. This evidence concerns the gene STAT3 and Hepatic fibrosis.