In the subsequent analysis, 196 hub genes associated with liver fibrosis were identified, including AKT1, IL6, TNF, TP53, VEGFA, JUN, IL1B, EGFR, CASP3, PTGS2, MYC, ESR1, STAT3, HIF1A, MMP9, and EGF. The gene discussed is HIF1A; the disease is Hepatic fibrosis.