CLL-1, also known as C‐type lectin domain family 12, member A (CLEC12A), has been identified as a marker for leukemic stem cells as it is present on the surface of CD34+CD38- cells in AML patients but can not be found on CD34+CD38 cells from healthy individuals (94, 95). This evidence concerns the gene CLEC12A and acute myeloid leukemia.