IL17A and cardiovascular disorder: IL-17A is highly significant, as it has been shown to directly contribute to the pathogenesis of cardiovascular diseases including hypertension (Kamat et al., 2015; Madhur et al., 2010; Madhur et al., 2011; Saleh et al., 2016; Kuwabara et al., 2017; Nguyen et al., 2013).