SPRY4 and obesity due to melanocortin 4 receptor deficiency: Through integration of previous research findings with GO and KEGG enrichment results, we identified seven key candidate genes potentially influencing early growth traits in IMCGs: ZN845, SOX15, FGF11, GPS2, DVL2, SPRY4, and STAT2. Considering that weight gain in animals is closely associated with muscle development, fat deposition, and obesity (3), Functional enrichment analysis was conducted for these seven candidate genes.