KEGG pathway analysis identified 160 significantly enriched pathways, including cancer pathways, chemical carcinogenesis–receptor activation, cardiovascular disease, Kaposi sarcoma–associated herpesvirus infection, lipid and atherosclerosis, PI3K–AKT signaling, AGE–RAGE signaling in diabetic complications, MAPK signaling, prostate cancer, and HIF-1 signaling (Figure 1F). The gene discussed is AKT1; the disease is Familial prostate cancer.