A variety of fusion genes have been reported in ALK-rearranged IMT of the female genital tract, including IGFBP5, THBS1, FN1, TIMP3, TPM3, TPM4, EML4, CTCL, RANBP2, SEC31A, DES, and DCTN1 (14). The gene discussed is DES; the disease is inflammatory myofibroblastic tumor.