The meta-analysis for the predictive value of hs-CRP in incident CVD among adults with autoimmune diseases initially demonstrated high heterogeneity [Q(22) = 110.86, p = 0.00; I2 = 96.55%; τ2 = 0.09; H2 = 29.00], prompting the use of a random-effects model. The gene discussed is CRP; the disease is autoimmune disease.