Postmenopausal women with RA have a 1.5- to 2.5-fold higher risk of cardiovascular outcomes, including CHD, stroke, and CVD mortality.Inflammation markers (WBC count, IL-6) and joint pain severity were strongly associated with CVD outcomes.Anti-CCP and RF were not significantly associated with higher CVD morbidity or mortality​. This evidence concerns the gene IL6 and rheumatoid arthritis.