CRP and Crohn disease: Bio-naïve patients without active intestinal fistula, and with low inflammation burden (Crohn’s Disease Activity Index ≤ 220 and C-reactive protein ≤ 10 mg/L) showed the highest rates of steroid-free remission and objective remission at both time points (all P < 0.05), along with a superior therapeutic continuation (P < 0.001).