Specifically, ovarian cancer-secreted exosomal miR-141 activates the Yes-associated protein 1 (YAP1)/Growth-regulated oncogene-alpha (GROα)/Human C-X-C Motif Chemokine Receptors (CXCRs) signaling cascade, thereby enhancing the development of the PMN and ultimately leading to tumor metastasis [20]. Here, YAP1 is linked to ovarian cancer.