LGALS3BP and neuroblastoma: To assess the specificity and robustness of the method, the previouslydescribed ADC 1959-sss/DM4 was employed for in vivo detection andmonitoring of its released payloads, DM4 and S-Met-DM4.The primary human neuroblastoma cell line hNB, which lacks endogenousLGALS3BP expression, was used to generate an engineered variant ectopicallyoverexpressing a high level of human LGALS3BP.