WDR45 and neurodegeneration with brain iron accumulation: The initial case description of later-onset neurodegeneration was with BPAN (beta-propeller protein-associated neurodegeneration) in a case of WDR45 (WD repeat domain phosphoinositide-interacting protein 4, WIPI4), leading to neurodegeneration with brain iron accumulation (NBIA), which is a distinct disorder not only phenotypically but also genetically.