Concurrent upregulation of PLA2 isoforms (PLA2G2A, PLA2G5) and thromboxane receptor (TBXA2R) mRNA, alongside increased thromboxane B2 (TXB2; p = 0.005), suggested that PLA2-mediated release of free F2-IsoPs contributes to placental oxidative injury and hypertension in PE. Here, PLA2G2A is linked to Hypertension.