MSN and hematopoietic and lymphoid system neoplasm: Supporting these observations were the results obtained from qRT-PCR experiments, with msn (a marker of lamellocyte lineage) transcript levels elevated 8.19-fold in Ubc9−/− mutants and only 1.66-fold in the rescued larvae, relative to those in untreated Ubc9−/+ heterozygotes, supporting the decrease in blood tumors primarily composed of lamellocytes (Fig. 6E).