TREM2 and metabolic dysfunction-associated steatotic liver disease: In contrast, the TREM2+ macrophage population (clusters 3 and 8), which is associated with MASLD pathogenesis (41–43), remained unchanged between the 2 groups, with Bcl2AdTG mice having 1,171 TREM2+ macrophages and WT mice having 1,142 TREM2+ macrophages (Figure 5, A–C, and Supplemental Figure 9).