CXCL10 and diabetic kidney disease: Increased levels of cytokines such as IL-6, IL-8, IL-1β, TNF-α, and IFN-γ as well as chemokines including chemokine receptor 2 (CCR2), C-C motif chemokine ligand 2 (CCL2), CCL5 (RANTES), and C-X-C motif chemokine ligand 10 (CXCL10) have been observed in kidney tissue of rodent models of diabetes, as well as in plasma and serum of people with DKD (43).