As an epithelial‐derived key alarmin, TSLP drives the Th2 inflammatory cascade by activating dendritic cells, mast cells, and type 2 innate lymphoid cells (ILC2s), thereby contributing to shared pathophysiological mechanisms in severe asthma and CRSwNP [19, 20, 21]. Here, TSLP is linked to chronic rhinosinusitis with nasal polyps.