Its superior performance likely stems from its dual inhibition of IL‐4 and IL‐13 signaling via IL‐4Rα blockade, a mechanism validated in preclinical models where IL‐4Rα knockout mice exhibited reduced mucosal eosinophilia and polyp burden in house dust mite‐induced nasal polyposis [35]. The gene discussed is IL13; the disease is Increased total eosinophil count.