Interestingly, Foxp3YFP‐cremiR‐10afl/fl mice showed an increased intestinal barrier integrity compared with Foxp3YFP‐cremiR‐10afl/+ mice in the DSS‐induced chronic colitis model, as demonstrated by a higher level of IEC tight junction protein 1 (Tjp1) in Foxp3YFP‐cremiR‐10afl/fl mice (Figure S2C, Supporting Information). Here, TJP1 is linked to Chronic colitis.