TARDBP and melanoma: For example, T153/Y155 phosphorylation was found upon heat shock in HEK293T and SH‐SY5Y cells [41], and T88, S91/S92 phosphorylation in TDP‐43's nuclear localization signal (NLS) in HeLa cells upon EGF stimulation, in breast cancer cell lines as well as melanoma cells upon MKK1/2 inhibitor treatment, possibly to regulate TDP‐43's nuclear import [31, 42, 43, 44, 45].