For instance, targeted analysis of lung ECs isolated from mice and humans with pulmonary arterial hypertension (PAH) determined that there was a subpopulation of Car4+ lung capillary cells that became apoptotic, pro‐migratory, and upregulated pro‐angiogenic genes as part of the pulmonary hypertension (PAH) pathology (Rodor et al. 2022). This evidence concerns the gene CA4 and pulmonary arterial hypertension.