Cytopenias may indicate bone marrow dysfunction or autoimmune destruction, which can be found in many forms of PAD (e.g., PGM3 deficiency, WAS, WIP deficiency, ARPC1B deficiency, NOCARH, IPEX, STAT1 GOF). The gene discussed is FOXP3; the disease is hyperinsulinemic hypoglycemia, familial, 4.