Zhu et al. developed a predictive model for first failure after definitive CRT in inoperable locally advanced NSCLC, incorporating smoking history, pathology, tumor location, EGFR mutation status, age, tumor diameter, clinical N stage, consolidation chemotherapy, and radiation dose (Zhu & Fu 2019; Zhu et al. 2020). Here, EGFR is linked to non-small cell lung carcinoma.