MKI67 and neoplasm: This may occur because although sex is important factor in PTC epidemiology and prognosis aspects, its impact on the cellular proliferation is minimal, considering the Ki-67 expression is more closely related to intrinsic tumor characteristics [47] Although the multifocality in PTC tumors is known to have prognostic value for predicting disease recurrence rate [48], our finding corroborates prior studies [12, 36], in which we found no substantial differences in Ki-67 expression across different multifocality statuses of the tumors.