CD73 expression was significantly associated with female gender (OR = 2.74, 95% CI 1.07–7.01), tumor stage T2 (OR = 6.59, 95% CI 1.36–31.90) and T4 (OR = 9.13, 95% CI 1.68–49.66), mucoepidermoid carcinoma subtype (OR = 10.62, 95% CI 2.77–40.69), and higher Ki-67 levels (OR = 3.61 per 10% increase, 95% CI 1.26–10.31). The gene discussed is NT5E; the disease is mucoepidermoid carcinoma.