Consistent with the proteomic nuclear phenotype in BD there was also an enrichment of nuclear proteins, particularly those that interact with RNA, including RNA helicases (DDX23, DHX29, DHX30, and DHX57), integrator complex proteins (INTS3, INTS4) and RNA stability (CDC73, GTPB1, GTPB4). This evidence concerns the gene DHX29 and Behcet disease.