Activation of thispathway is frequently observed in breast cancer cells, contributingto increased cell proliferation, survival, and metastasis.−,  Inhibition of PI3K-Akt signaling has shown promise in suppressingbreast cancer growth both in vitro and in vivo., Moreover, targeting specific components of this pathway has emergedas a potential therapeutic strategy for breast cancer treatment., Here, AKT1 is linked to breast cancer.