To mitigate the immunopathological effects of malaria, monocytes and macrophages increase the expression of M2‐associated immunoregulatory factors, such as Heme Oxygenase‐1 (HO‐1) [136] and IL‐10 [136] which reduce both oxidative burst and inflammation but simultaneously heighten the risk of bacterial superinfections, particularly with non‐typhoidal Salmonella [137]. This evidence concerns the gene IL10 and malaria.