The minimal effect in the LNs, which contain very few mCD45+ cells, and the partial rescue of human T cells in both the SP and tumor with prior LC treatment, suggest the mouse myeloid cells are phagocytosing the human T cells following blockage of the SIRPα–CD47 macrophage tolerance pathway (Supplementary Fig. S2A and S2B). This evidence concerns the gene SIRPA and neoplasm.