AKT1 and cancer: Key pathways involved in cellproliferation, such as the mitogen-activated protein kinase (MAPK)/extracellularsignal-regulated kinase (ERK) and phosphoinositide 3-kinase (PI3K)/protein kinase B(AKT) pathways, have been studied across different cancer types, and the prevalenceof genetic mutations linked to these pathways has been observed in RAI-refractorythyroid cancer (7,8).