We collected data drug sensitivity information and SIRT1 mRNA expression data of various cancer cell lines from the CTRP database and found that the mRNA expression of SIRT1 negatively correlated with the IC50 of BI-2536, GSK461364, KW-2449, KX2-391, MK-1775, PX-12, axitinib, daporinad, indisulam, teniposide, tivantinib, and vincristine (|R| > 0.30, FDR < 0.05) (Table 3). Here, SIRT1 is linked to cancer.