For example, TMP protects rats against cerebral ischemia-reperfusion injury via activating PI3K/Akt pathway (Ding et al., 2019); TMP ameliorates cognition of Alzheimer’s disease mice model by inhibiting ubiquitination of somatostatin receptor 4 (SSTR4) (Weng et al., 2021); TMP promotes the repair of spinal cord injury by alleviating ferroptosis (Liu et al., 2024). This evidence concerns the gene SSTR4 and Cerebral ischemia.