Additionally, biomarkers associated with resistance to Sotorasib in KRAS G12C-mutated lung adenocarcinoma, including solute carrier family 2 member 1 (SLC2A1), transducin-like enhancer protein 1 (TLE1), family with sequence similarity 83 member A (FAM83A), high mobility group AT-hook 2 (HMGA2), F-box protein 44 (FBXO44), and MT-RNR2-like 12 (MTRNR2L12), are linked to abnormal PD‐L1 expression (Lin et al., 2024). Here, HMGA2 is linked to lung adenocarcinoma.