It was found that PCA could restore the mRNA expression levels of PPARα and PPARγ in renal tissue, reduce the concentrations of advanced glycation end product receptor (RAGE), advanced glycation end product (AGEs) and glycated albumin, and promote the reconstruction of PPARγ expression in diabetic mice, improve renal metabolic homeostasis and reduce DKD damage (85). Here, AGER is linked to diabetic kidney disease.