The prolapsed bowel appeared mildly congested but not severely oedematous, and there was no associated anal fissure. Laboratory investigations demonstrated a hemoglobin of 11.8 g/dL (baseline ~10 g/dL) and a white blood cell count of 8.34 ×109/L. Tumor markers were within normal limits, with CA 19-9 at 15.62 U/mL and CEA at 0.0 ng/mL (Table 1). The gene discussed is CEACAM5; the disease is neoplasm.