SGLT2i, Sodium-Glucose Cotransporter 2 inhibitors; DM, Diabetes Mellitus; T1DM, Type 1 Diabetes Mellitus; T2DM, Type 2 Diabetes Mellitus; DKA, Diabetic Ketoacidosis; eKA, Euglycemic Ketoacidosis; euDKA, Euglycemic Diabetic Ketoacidosis; VA, Veterans Affairs; CABG, Coronary Artery Bypass Grafting; NR, Not Reported; HCO3, Bicarbonate; CO2, Carbon Dioxide; JBDS, Joint British Diabetes Societies; AACE, American Association of Clinical Endocrinology; ACE, American College of Endocrinology; UAE, United Arab Emirates. The gene discussed is SLC5A2; the disease is type 2 diabetes mellitus.