For example, a patient with SHFM1 and sensorineural hearing loss (SNHL) was found to carry a 6.3 Mb deletion at 7q21.13-q21.3 (chr7: 89,993,838–96,278,971, hg19), which did not remove DLX5/6 but removed DYNC1I1 exons 15 and 17 along with other genes (Ambrosetti et al., 2023). Here, DLX5 is linked to sensorineural hearing loss disorder.