When focusing on the overall survival (OS), BMP4 was a significant hazard factor for adrenocortical cancer (ACC), pancreatic cancer (PAAD), and pheochromocytoma & paraganglioma (PCPG) and a beneficial factor for breast cancer (BRCA), acute myeloid leukemia (LAML), lower grade glioma (LGG), and stomach cancer (STAD). This evidence concerns the gene BMP4 and hereditary pheochromocytoma-paraganglioma.