ADAR1 also impairs tumor suppressors [e.g., filamin B in triple-negative breast cancer, bladder cancer associated protein (BLCAP) in cervical cancer, and Nei-like DNA glycosylase 1 (NEIL1) in multiple myeloma], promoting proliferation, invasion, signal transducer and activator of transcription 3 (STAT3) activation, or genomic instability (81–83). Here, NEIL1 is linked to AL amyloidosis.